America’s leading food and drug regulator might ban online sales of e-cigs — a move that could threaten brands like Juul

By Erin Brodwin, Business Insider, September 25, 2018

With comments from Nicholas Chadi

At a breakfast meeting with journalists on Tuesday, Food and Drug Administration commissioner Scott Gottlieb said the agency is considering a ban on online sales of e-cigs. The move would include barring popular e-cig startup Juul, recently valued at $15 billion, from selling its products over the internet.

Juul, which currently dominates the e-cig market, has faced a growing backlash from public health advocates and researchers over claims that it marketed to teens. […]

Nicholas Chadi, a clinical pediatrics fellow at Boston Children’s Hospital, spoke about the Juul at the American Society of Addiction Medicine’s annual conference in April.

“After only a few months of using nicotine, [these teens] describe cravings, sometimes intense ones. Sometimes they also lose their hopes of being able to quit,” Chadi said. (Read more)


An explainer of a new marijuana-based pharmaceutical drug approved by FDA

By Dr. Amitha Kalaichandran, ABC News, June 26, 2018
With comments from Nicholas Chadi

Epidiolex, a medication formulated from a cannabidiol (CBD) substance derived from the marijuana plant was approved by the U.S. Food and Drug Administration (FDA) for children and adults over the age of 2. It treats Dravet syndrome and Lennox-Gastaut syndrome (LGS), two rare epilepsy disorders that primarily affect children. […]

Dr. Nicholas Chadi, a pediatrician completing his fellowship at Boston Children’s Hospital in pediatric and adolescent addictions, points to the limited research on CBD side effects in general.

“Only recently have we been able to separate CBD from THC, and to create substances with very high CBD content,” Chadi told ABC news. “So we don’t really know much about the effect of CBD on the developing brain or whether it could be addictive in the long run.” (Read more)

A pediatrician’s take on Mindfulness, Marijuana, and Music

The Happy Doc Podcast – Episode #57

June 24, 2018

Interview with Happy Doc host: Dr. Taylor Brana

This 57th episode of The Happy Doc Podcast features an interview by Dr. Taylor Brana with Dr. Nicholas Chadi M.D., who shares his medical journey. He talks about addiction medicine, his advice to teens about marijuana use, a mindfulness practice involving washing your hands, Why life doesn’t end with medical school, and what makes Nicholas Chadi feel fulfilled. Featuring music from The Eight Tracks a cappella. (Listen to the full episode of the Happy Doc here)

Vaping: More than just blowing smoke

New England Psychologist, June 13, 2018
With comments from Nicholas Chadi

In 2015, the Centers for Disease Control and Prevention (CDC) conducted a National Youth Tobacco Survey and found that 2.39 million teens are “vaping” (i.e., using an electronic smoking device). As this trend continues to grow, parents, schools and health professionals struggle with ways to effectively address the problem. […]

Nicholas Chadi, M.D., pediatrician specializing in Adolescent Medicine, and first and only Pediatric Addiction Medicine Fellow in North America, is currently involved in the Adolescent Substance Use and Addiction Program (ASAP) at Boston Children’s Hospital. He reported that vaping has serious negative physical consequences.

In the past two months, leading pediatric journals have published two studies that show e-cigarettes contain multiple cancer-causing substance and heavy metals that scar the lungs, according to Chadi. Read more

Vaping, JUULing and e-cigarettes: what teens and parents need to know

By Nicholas Chadi, Thriving, May 8, 2018

“Which flavor is this? Cherry cheese cake? French vanilla? Crème bruléee?” If you are a teen in high school these days, chances are that you’ve already asked yourself this question and have inhaled at least a few breaths of some of the powerful scents coming from a JUUL or other type of e-cigarette.

The popularity of electronic cigarettes has increased exponentially in the past five years: nearly one in three seniors in high school say that they have used an e-cigarette in the past year. The FDA has recently released a statement warning about the risks of vaping and supporting strict regulations to avoid exposure to e-cigarettes for children and teens. But are e-cigarettes all that bad? Read more

Experts are calling out a vape pen with ‘scary’ nicotine levels that teens love — here’s how it affects the brain

Business Insider, April 19, 2018
With comments from Nicholas Chadi

“The Juul is a new trend I’m afraid,” Nicholas Chadi, a clinical pediatrics fellow at Boston Children’s Hospital, said at the American Society of Addiction Medicine’s annual conference last week. “We get calls from parents across Boston wondering what to do about this.”

The crux of the problem centers on what nicotine does to the teen brain — especially in an area called the prefrontal cortex, which plays a key role in emotional control, decision making, and impulse regulation.

Brain imaging studies of adolescents suggest that those who begin smoking regularly at a young age have markedly reduced activity in the prefrontal cortex and perform less well on tasks related to memory and attention compared to people who don’t smoke. Chadi said these brain changes are also linked with increased sensitivity to other drugs as well as greater impulsivity. Read more 

Easing access to marijuana is not a way to solve the opioid epidemic

By Nicholas Chadi and Sharon Levy, STATnews – April 12, 2018

The take-home message from research published last week in JAMA Internal Medicine — let’s liberalize access to marijuana as a way to address the raging opioid epidemic — captured the public imagination. We disagree. Supporting medical or recreational marijuana as an alternative to opioids for conditions like chronic pain is a bad idea, especially for America’s youths. Read more

Facebook Live: Celebration = Intoxication is a dangerous message for youth

Boston Children’s went live with experts from the Adolescent Substance Use and Addiction Program (ASAP) to discuss adolescent substance abuse and what families and providers can do to help. View the full discussion.

Expert panel:

-Nicholas Chadi, MD: Pediatrician specialized in Adolescent Medicine and Addiction Medicine Fellow

-Diana Deister, MD: Child and Adolescent Psychiatrist for ASAP

-Shannon Mountain-Ray: Clinical Social Worker and Director of Social Work for ASAP

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